There are infusion fertility “add-ons” that are sometimes offered before starting fertility treatment. In this article, we will explain how the infusion works and if it should be used as an add-on for fertility treatment.

A lipid (fat)-based infusion is given to help with embryos implanting on the uterine lining (endometrium). The infusion is a solution made up of soybean oil, egg yolk phospholipids and glycerin, which is thought to help regulate NK (natural killer) cells. Regulation of NK cells is involved in embryo implantation.

If you’ve had miscarriages or recurrent implantation failure (transfer of three top-quality embryos in optimally managed cycles), you may have been given the option to try an infusion.

Should the infusion be used?

Current studies show that more research is required. Live birth may be increased but there may be more congenital (birth) defects in women having infusions of lipid at the time of fertility treatments.

"Add-ons" need to have three criteria met to be used at Care Fertility 

  1. Some preliminary evidence of benefit
  2. Biologically plausible
  3. No evidence of harm.

The first and second criteria may be met for infusion of lipid but until the evidence of safety for the babies born is certain, Care Fertility prefers to offer proven and safer options for miscarriage and recurrent implantation failure.

Read the recent studies performed to date. 

If you are struggling with miscarriage or recurrent implantation failure, read more about when to seek help after having a miscarriage or if EmbryoGlue or Preimplantation Genetic Testing could be suitable for you.